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What
is Prospective Medicine?
Why is it called
P4 Medicine TM ?
Prior to the 20th century, biomedical science could be characterized as symptomatologic
medicine, as illnesses were identified and treated based upon external
symptoms and disease manifestation. Discoveries in the 20th century allowed
for a better understanding of the underlying causes of many
diseases, particularly those driven by external pathogens, such as
viruses and bacteria. Treatments for disease, although based on an
understanding of human biology, could be described as reactive
medicine, with treatments applied once symptoms had manifested.
Furthermore, therapies were often developed by happenstance
(penicillin) or through random application of compounds against a
disease.
Prospective Medicine, in which the latest technologies are applied
to understand biology and disease, is anticipated to be the medicine
of the 21st century. The focus of this approach to medicine is to
gain an understanding of the origins of disease at the genomic level
and to translate this knowledge into patient applications. |
Friendster for Proteins
Forbes.com
Robert Langreth and Matthew Herper
03.12.07
Understanding how the body's tiny components communicate
is opening up vast territory in drug research.
Peter Sorger spent eight years developing new laboratory gadgets
and arcane mathematical theorems to explain how networks of
genes and proteins can go awry, causing cancer, arthritis and
other diseases.
more.....
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The growing
knowledge of the genome sequence and the technology used to assess
gene and protein expression are among the tools the ISM will employ
to understand disease from a molecular through the physiological
level.
Predictive,
Preventive, Personalized & Participatory
(P4 Medicine TM)
Prospective medicine is embodied by Predictive, Preventive, Personalized and
Participatory (P4 Medicine TM) medicine. This shift in medicine will allow patients to
partner with doctors to become more participatory in the management of their
care. New diagnostic and treatment choices that are proactive rather than
reactive will be available through a variety of tools already on the
near-term horizon. Such tools will allow physicians to analyze an
individual's genetic composition and forecast a single patient's health.
And, because prevention is less expensive than reactive medicine, a focus on
wellness will emerge with the progress of prospective medicine. The ISM
ascribes the future of health care to prospective medicine and will play a
substantial role in bringing these modalities to the forefront of health
care in the United States and throughout the globe. |
4 New Ps in Medicine
-
Predictive
Medicine
refers to the
development of a probabilistic health projection for a person
based on their DNA and protein expression.
-
Preventative
Medicine
denotes the
creation of therapeutics that will prevent a disease that a
person is assessed to have a high probability of developing.
-
Personalized
Medicine
refers to treating an
individual based on their unique human genetic variation,
complementing the predictive and preventative efforts above
-
Participatory Medicine
denotes a
patient's active, informed involvement in their medical choices
and care, acting in partnership with their health providers.
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